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Image for: RNA modification is responsible for the disruption of mitochondrial protein synthesis in Alzheimer's disease


Elevated TRMT10C protein levels in Alzheimer’s disease result in methylation of mitochondrial mRNA and subsequently in the suppression of the synthesis of a subunit protein of complex I of the respiratory chain; the outcome is mitochondrial dysfunction.
Elevated TRMT10C protein levels in Alzheimer’s disease result in methylation of mitochondrial mRNA and subsequently in the suppression of the synthesis of a subunit protein of complex I of the respiratory chain; the outcome is mitochondrial dysfunction.

ill./©: Kristina Friedland / JGU

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