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Image for: Researchers Discover new Key Function of an Enzyme in the Nervous System


Section through nerve fibres within the sciatic nerve as seen under the electron microscope: the axons (nerve cell projections, pink) are only poorly surrounded by a myelin sheath (generated by Schwann cells, coloured blue) following inactivation of the gene encoding BACE1, which controls the myelination process (right panel). The nerve fibres in a control animal (left panel, BACE1 gene is intact) are in contrast surrounded by thick myelin sheaths (dark rings).
Section through nerve fibres within the sciatic nerve as seen under the electron microscope: the axons (nerve cell projections, pink) are only poorly surrounded by a myelin sheath (generated by Schwann cells, coloured blue) following inactivation of the gene encoding BACE1, which controls the myelination process (right panel). The nerve fibres in a control animal (left panel, BACE1 gene is intact) are in contrast surrounded by thick myelin sheaths (dark rings).

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