BEGIN:VCALENDAR
METHOD:PUBLISH
BEGIN:VEVENT
CATEGORIES:idw
STATUS:TENTATIVE
DTSTAMP:20120524T115842
ORGANIZER:MAILTO:uwe.bornscheuer@uni-greifswald.de
DTSTART:20120531T170000
DTEND:20120531T183000
SUMMARY:Recognition codes, scaffold design and ligation of protein adaptor domains
DESCRIPTION:Ernst-Moritz-Arndt-Universität Greifswald\NDas Institut für Biochemie
	 lädt gemeinsam mit dem Ortsverband der Gesellschaft Deutscher Chemiker
	 zu einem Kolloquium der GDCh. Prof. Dr. Christian Freund von der Freien
	 Universität Berlin\, Institut für Chemie und Biochemie\, Protein
	 Biochemie spricht zum Thema: “Recognition codes\, scaffold design and
	 ligation of protein adaptor domains”\N\NAbstract: Intracellular protein
	 adaptor domains play an ubiquitous role in the formation of proteins
	 assemblies inside the cell. With a focus on proline-rich sequence
	 recognition domains phage display was used to decipher the recognition
	 code of several of these domains. Subsequently it could be shown that
	 peptides derived from these studies represent useful tools in SILAC/MS
	 experiments that are meant to decode the corresponding interactomes.
	 Furthermore\, certain adaptor domains can form the basis to design
	 scaffolds with novel binding properties. Finally\, sortase-mediated
	 protein ligation can be invoked to investigate multidomain adaptor
	 proteins in regard to specific structural and mechanistic
	 questions.\N\N\N\Nuwe.bornscheuer@uni-greifswald.de\N\Nhttp://www.chemie
	 .uni-greifswald.de/\N
CLASS:PUBLIC
URL:http://www.idw-online.de/en/event39828
UID:idw-event-39828
LOCATION:Großen Hörsaal der Biochemie  17489 Greifswald\, Felix-Hausdorff-Straße 
 4  Mecklenburg-Vorpommern Germany
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